VISDB Viral Integration Site DataBase

VIS ID

TVIS10011453

Fusion event

HBV-SERPINC1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1754

Orient

-

Integrated sequence

CATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGA| |TTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCA

Chromosome

chr1

Cytoband

q25.1

Reference genome

Start

End

173883981/173914843 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6865-3p ; hsa-mir-4446-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-1306-5p ; hsa-mir-6741-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-934 ; hsa-mir-3618 ; hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-149-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-6812-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-181c-3p

Nearest miRNA

hsa-mir-101-1/Upstream/1770199; hsa-mir-1182/Downstream/2053527;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/46064, chr1-CpG: 93/Downstream/106824

Upstream sequence

GGATCTTCTGTTCTGAGCCCTCATCCTCAGTTGCCTTCTTCTCCGGGGAGCGGTAAATGCACATGGGATTCATGGGAATGTCCCGCGGCTTGGCTGTGCA

Downstream sequence

GATGTCCACAGGGCTCCCGTGACAGGTCACGCAGTCCCAGAAGCCAATGAGCAGCAAGGACAAAAGATAAACCTTCCTGCAAGGAGACAAAATGCCAAGT