Basic Information
VIS ID
TVIS10011459
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1777
Orient
-
Integrated sequence
AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTA| |GGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAA
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
39218401/38752729 (Hg38)
End
39218401/38752729 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12136/Upstream/663400; hsa-mir-101-1/Downstream/2001626;
Nearest TSS
ENST00000473358/Upstream/277533; ENST00000456813/Downstream/21779;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/43461, chr1-CpG: 72/Downstream/51328
Nearby gene
LINC01343(-537962) ; RRAGC(+86614) ;
Upstream sequence
GCTAACACCATCCACAGTTCCTCCcatatctctacacatgagctgctcttcacttcaagaggtgaagactattttccctccccttgaatctgggtggacc
Downstream sequence
tgggggcaccttcacagaTTCTGAACATGATTTGCAGCTCTGCTCACCACCATTACTTTTCCCTCTCACCTGGGGTTCTAAGGTAGCCTGGTATTAGAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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