Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011470
Fusion event
HBV-AGAP11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1810
Orient
-
Integrated sequence
CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
Start
End
88741281/86981524 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1265/Upstream/716736; hsa-mir-107/Downstream/522357;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/9649, chr10-CpG: 19/Downstream/28153
Upstream sequence
accttcctctggagcctcagtaaatttattttatctagatgggtccaggtgctgcaggtgattacccttatcttgtctcctgcaaaatcatggaggtttg
Downstream sequence
gggaattctttagacttcctctcgtgtggaggtttgttttcttcTTTTTTCTTTCCTGCAAGGACAAAGTGAATTCTGTGATGGTTTATGTATCATTTTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.