Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011473
Fusion event
HBV-C11orf88 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1731
Orient
-
Integrated sequence
ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
End
111395633/111524908 (Hg38)
Orient
+
Location type
Exonic
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/11393; hsa-let-7a-2/Downstream/1925115;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9921, chr11-CpG: 110/Downstream/15299
Upstream sequence
TGTTGATATAAACTTTGATGAACAGCTTTTTAAAGAAAATGTGCATAttttctttttcttttctttttttttagacaaggtctcactctgtcacccagaa
Downstream sequence
tgaagtgcagtggcatgatcatggctcactgcagcctcaactttctcggattcaggtgattctcccacctcagcctcagcctccaaagtttctgggacta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.