Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011474
Fusion event
HBV-C11orf88 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1940
Orient
+
Integrated sequence
TCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGT| |GGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAG
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
End
111395704/111524979 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/11464; hsa-let-7a-2/Downstream/1925044;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9992, chr11-CpG: 110/Downstream/15228
Upstream sequence
tagacaaggtctcactctgtcacccagaatgaagtgcagtggcatgatcatggctcactgcagcctcaactttctcggattcaggtgattctcccacctc
Downstream sequence
agcctcagcctccaaagtttctgggactacaggtgcacaccatcacatccagctacattttttgtattttttgtagaggcagggttttgccatgttgccc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.