Fusion event
HBV-JAML integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
CTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGA| |CCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATA
End
118073330/118202615 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/4752527; hsa-let-7a-2/Downstream/441385;
Upstream sequence
CTCTGCCTCAGGATGGCAGGGCAGAGATAAGAATGGGGGAGACATAGATATGTTTGTGGGTGGAGAAGCTGCATGAGCCCCCATAATGGCTCGATTTTCT
Downstream sequence
CTGTGAATTGGACTTCTGAGAAGGAAGCACACAGACCTGCCGTGCTCCCCTCTCCAGCTGGAGACAAGGTGCCTCCACAGACTTAGGTCTCTGGCCTGAG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.