Basic Information
VIS ID
TVIS10011485
Fusion event
HBV-LOC107984506 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1932
Orient
+
Integrated sequence
CTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGA| |GCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGT
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
15210049/15057115 (Hg38)
End
15210049/15057115 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107984506
Nearest miRNA
hsa-mir-1244-3/Upstream/2141197; hsa-let-7i/Downstream/2616184;
Nearest TSS
ENST00000382841/Upstream/55282; ENST00000541243/Downstream/81048;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/253578, chr12-CpG: 49/Downstream/163937
Nearby gene
PDE6H(-75250) ; RERG(+50667) ;
Upstream sequence
taggaggctgaggcaggagaatcgcttgaacctgggaggtggaggttgcagtgagccaagattgcgccattgcactccagcctgggcaacaagagagaaa
Downstream sequence
ctccgtctcaacaacaacaacagaaaaaaaGATTAACTGAATGAagtgtagatattagtgtcttattctaaaaacaggtatttgaagctatgagaagctg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate