PLEKHA5 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011486
Fusion event
HBV-PLEKHA5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1801
Orient
-
Integrated sequence
GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
End
19377379/19224445 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/1551051; hsa-let-7i/Downstream/4987976;
Upstream sequence
TGGAAGTCTGGTTTAATTGAATGACttttgtttttgtttttgtttttTTCCTGGGCAGAATTCTACCATTAACTTCTTTTCCCACTCACTTGCCCATTAT
Downstream sequence
CAGTGGGTTTTGCTCTTACATGGTATAAACCAGTTTTCTGCATTTCATAGTAAAACATTATCCCAAGGAACACCTACCTTCTTTACAACCAAATAGGGCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate