Fusion event
HBV-PLEKHA5 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG
End
19377379/19224445 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/1551051; hsa-let-7i/Downstream/4987976;
Upstream sequence
TGGAAGTCTGGTTTAATTGAATGACttttgtttttgtttttgtttttTTCCTGGGCAGAATTCTACCATTAACTTCTTTTCCCACTCACTTGCCCATTAT
Downstream sequence
CAGTGGGTTTTGCTCTTACATGGTATAAACCAGTTTTCTGCATTTCATAGTAAAACATTATCCCAAGGAACACCTACCTTCTTTACAACCAAATAGGGCC
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.