PTPRR _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011492
Fusion event
HBV-PTPRR integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1801
Orient
-
Integrated sequence
GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
71184264/70790484 (Hg38)
End
71184264/70790484 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTPRR
miRNAs that regulate target gene
hsa-mir-150-5p
Nearest miRNA
hsa-let-7i/Upstream/1205661; hsa-mir-1178/Downstream/8628773;
Nearest TSS
ENST00000382841/Upstream/1502; ENST00000549015/Downstream/130359;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/180207, chr12-CpG: 104/Downstream/648928
Upstream sequence
ctttcctgcctaggcttccagggtgccacactttcttagtttttcttctcattggccattccttttcaagttccctttgcttatttgtcctcatcttcct
Downstream sequence
cacctctatacaatggacagcccaatgctcaattcttagtctcttcttttcctctatagtctgaaatttagcaggatctctcccttagaactcaagactc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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