VISDB Viral Integration Site DataBase

VIS ID

TVIS10011506

Fusion event

HBV-TTC7B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2410

Orient

+

Integrated sequence

GCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAAT| |CGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTAC

Chromosome

chr14

Cytoband

q32.11

Reference genome

Start

End

91234161/90767817 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-9-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-1260a/Upstream/13501527; hsa-mir-1185-1/Downstream/3180409;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/9052, chr14-CpG: 87/Downstream/48066

Upstream sequence

agaacaaacagaaaaaaagattgaagaaaagtgaacagagcctaagaaacatgtggaacaccatcaagagaactaacatatgtattgtgggaattataga

Downstream sequence

aggaaaagagggagagaaaggagcagagaggatatttgaagaaatagtgactgaaaacttttgaaatttggtgaaagatattaagtgaaaagtacaatta