VISDB Viral Integration Site DataBase

VIS ID

TVIS10011522

Fusion event

HBV-RSPRY1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2002

Orient

+

Integrated sequence

ATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCG| |CCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGAC

Chromosome

chr16

Cytoband

q13

Reference genome

Start

End

57224332/57190420 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-21-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-1225/Upstream/286067; hsa-mir-11401/Downstream/581869;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/3749, chr16-CpG: 70/Downstream/54474

Upstream sequence

gcattccagcctgggtgacagagcaacaccctgtctcaaataaataaaTAGGAAATGTTCTGTATTTTTTAGTAGGATACTTGTAAAGTGGGGTGTGATA

Downstream sequence

GTCTCAGGATTGCAAAATAAGTGGAAAGTCAGTAGTCACCACAAATGGGAAACACAGTGGAACCAGCAATCTATTTCAAAAGAATTATTTGGGGATAATA