VISDB Viral Integration Site DataBase

VIS ID

TVIS10011524

Fusion event

HBV-DNAH9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1816

Orient

-

Integrated sequence

CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

11709029/11805712 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-665 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-5582-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4451 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4468 ; hsa-mir-6840-3p ; hsa-mir-4459 ; hsa-mir-4756-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-129-5p ; hsa-mir-4524a-3p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-4797-5p ; hsa-mir-5007-5p ; hsa-mir-7855-5p

Nearest miRNA

hsa-mir-1253/Upstream/3618708; hsa-mir-10226/Downstream/276187;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/206701, chr17-CpG: 67/Downstream/191413

Upstream sequence

tcttggctcactgtaacctgtaacctccgcctcctatgatcaagagatactcctgcctcagctgccctagcaggtgggattacaagcactcaccaccatg

Downstream sequence

cctgctaatttttgtgtttttgtggacacagggtttcaccatgttggccaggctggtctcgaactcctaacctcaggtgatccccccaccttggcttccc