Basic Information
VIS ID
TVIS10011532
Fusion event
HBV-LINC01630 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1822
Orient
-
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
48954670/51428300 (Hg38)
End
48954670/51428300 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01630
Nearest miRNA
hsa-mir-1-2/Upstream/1301737; hsa-mir-122/Downstream/1808801;
Nearest TSS
ENST00000575820/Upstream/36258; ENST00000635103/Downstream/132521;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/230245, chr18-CpG: 29/Downstream/913707
Upstream sequence
AATGAGTAGATTCCAAGGCATGGCAGGGAGGAGAATATGACAAGGACaacagctaccagtagtcaccattcctacttctgttcctatttcctctttaacc
Downstream sequence
aactctaaacagatttttatctccactcatcttgaaatcttctcttggcaaggtcacccatgacatctaaattgccaaattcaatgatcatttcaaagat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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