VISDB Viral Integration Site DataBase

VIS ID

TVIS10011535

Fusion event

HBV-ZNF236 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1814

Orient

+

Integrated sequence

GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC

Chromosome

chr18

Cytoband

q23

Reference genome

Start

End

74678989/76967033 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-128-3p ; hsa-let-7e-5p ; hsa-mir-4732-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-6783-5p ; hsa-mir-548n ; hsa-mir-6872-3p ; hsa-mir-670-3p ; hsa-mir-6836-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-4797-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-660-3p

Nearest miRNA

hsa-mir-1-2/Upstream/4113651;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/46944, chr18-CpG: 17/Downstream/12273

Upstream sequence

TGCATTTTGCGGGTGTGATTTGATTGTTCGAGGTGGTATGCTCTGTGAGATCTGTGGTTTGTTTGGTTGTTGGAGGTGATGTGATTCGTGAAATGTGTTA

Downstream sequence

TTTGGTTGTTGGAGGTGATGTGATTCGTGAGATGTGTTATTTGGTTGTTGGAGGTGATGTGATTCGTGAGATGTGTTATTTGGTTGTTGGAGgtgatgtg