DTNB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011554
Fusion event
HBV-DTNB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1760
Orient
-
Integrated sequence
AGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGT| |TAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCT
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
End
25643688/25420819 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1301/Upstream/92098; hsa-mir-10b/Downstream/2575548;
Upstream sequence
tgatccgcctaccttggcctcccaaagtgttgggattacaggtgtgagccactgcacctggccGGTCTCTGTCTTTTAGAACCTTATGGTGATGGAACAC
Downstream sequence
AGAGCAGGCACTTGCTGGCTATTAGCTGACTGCCCAAATGAATGCACTATCAGACACTGCAGGAAAAAGGATAAAGAGAACACTTTCAAGTTTCTCTTTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate