VISDB Viral Integration Site DataBase

VIS ID

TVIS10011562

Fusion event

HBV-LBP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1799

Orient

-

Integrated sequence

GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG

Chromosome

chr20

Cytoband

q11.23

Reference genome

Start

End

36973937/38345534 (Hg38)

Orient

-

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-22-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/2891437; hsa-mir-1-1/Downstream/171029;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/84494, chr20-CpG: 56/Downstream/89348

Upstream sequence

gttgcagcgagcgatgttcatgccactggactcctgcttgagcaacagagtagactttgtctcaaaaaatgaaaaaagaaaaaaaaaTTGTACGTATCAA

Downstream sequence

CAAGCAAAAACTTTTTTAACACTTATAATTCTACCCCCACAACCAGAGACAATGCCTCATGACTCCTTGCTAAATATTTTCCAGATTGTTGAACATAGAA