VISDB Viral Integration Site DataBase

VIS ID

TVIS10011564

Fusion event

HBV-SEZ6L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

-

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr22

Cytoband

q12.1

Reference genome

Start

End

26575253/26179287 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-552-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-5591-3p ; hsa-mir-3938 ; hsa-mir-1273d ; hsa-mir-3133

Nearest miRNA

hsa-mir-1286/Upstream/723576; hsa-let-7a-3/Downstream/375925;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/9267, chr22-CpG: 90/Downstream/249701

Upstream sequence

agaccagcctgggcaacatggcaaaaccccatctgtacaaaaaattctaaaaattagccaggtgtggtggcatatgcctgtagtcccagctactcaagag

Downstream sequence

gctgagatggggggatccactgcagcccaggagtccaaggctgcagtgagctatgactgcaccactgcactctagcctgagtgacagagcaagaccttgt