Fusion event
HBV-chr22 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
CAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCT| |AGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTG
End
49785641/49391991 (Hg38)
Nearest miRNA
hsa-let-7a-3/Upstream/611638; hsa-mir-12114/Downstream/151402;
Upstream sequence
AGAGCAGTCATCGCCATTCTTGTCTATGTTCACTCAGAATGACCCACAAAAATACACCTGCCCACGTGCCAGAGCGACCCTCCCTGGCCAGGCCGGGCAT
Downstream sequence
GAATGGAAGGCATGAGCATTTGAGACACTAAATTGAGATTACAGGATCAACCCCTGTAAAGCTAGGAGGCAGAAGCCAATGTGGAAATTGGAATTACTTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.