VISDB Viral Integration Site DataBase

VIS ID

TVIS10011569

Fusion event

HBV-MBNL1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1799

Orient

-

Integrated sequence

GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG

Chromosome

chr3

Cytoband

q25.2

Reference genome

Start

End

152169121/152451332 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-mir-92b-3p ; hsa-mir-221-3p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-513a-3p ; hsa-mir-576-5p ; hsa-mir-590-3p ; hsa-mir-936 ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-491-3p ; hsa-mir-590-5p ; hsa-mir-1301-3p ; hsa-mir-4660 ; hsa-mir-5047 ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-let-7f-2-3p ; hsa-mir-19a-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-548aw ; hsa-mir-153-5p ; hsa-mir-552-5p ; hsa-mir-3161 ; hsa-mir-138-2-3p ; hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-4714-3p ; hsa-mir-4775 ; hsa-mir-6867-3p ; hsa-mir-101-3p ; hsa-mir-203a-3p ; hsa-mir-4694-3p ; hsa-mir-218-5p ; hsa-mir-144-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-4445-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-4482-3p ; hsa-mir-628-5p ; hsa-mir-8075 ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-520d-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520e ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-302a-3p ; hsa-mir-8064 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4693-5p ; hsa-mir-4711-3p ; hsa-mir-4330 ; hsa-mir-6832-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-5680 ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-5197-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-3591-5p ; hsa-mir-374b-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3124-3p ; hsa-mir-877-3p ; hsa-mir-6760-3p ; hsa-mir-889-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-5583-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-580-3p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-500a-5p ; hsa-mir-10b-5p

Nearest miRNA

hsa-let-7g/Upstream/885337; hsa-mir-1224/Downstream/6831314;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/181796, chr3-CpG: 120/Downstream/383481

Upstream sequence

ccagaaggagaggcagcgtggtcttgccaagatctttcttttagacttctagctctagatctttgaaagactaaatttctcttgttttgagccacccagt

Downstream sequence

GGATTTAATATGGACATTACCCATCTAAGCATCATTCAACCATACAtccatccatcctcctatcattctgttctcccctttcctttcctctctttatcct