Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011580
Fusion event
HBV-CLASP2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
Start
End
33723873/33682381 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12127/Upstream/1175992; hsa-let-7g/Downstream/2062095;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/241009, chr3-CpG: 86/Downstream/35333
Upstream sequence
GTATAATTTATAATTTTTGTCTTTTCTCTTGTGTTATATGTACAACTGCATTTATGCACCAAGTTGGAATTATATAGTACATATTTTCTTTGAAAATAAA
Downstream sequence
gggtaagtagtctagggtgtaacacaaaaaactggatacacactgataattgtttaaaccaagtaataggtaaatgaaggttcattattttattccacct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.