Basic Information
VIS ID
TVIS10011589
Fusion event
HBV-RPL34-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
109480641/108559485 (Hg38)
End
109480641/108559485 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
RPL34-AS1
Nearest miRNA
hsa-mir-12113/Upstream/7229071; hsa-mir-1243/Downstream/929213;
Nearest TSS
ENST00000502981/Upstream/390529; ENST00000503574/Downstream/60910;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/386095, chr4-CpG: 30/Downstream/91052
Upstream sequence
ctgcactccagcctgagcaaggggagcgagactccatcttaaaaaaaaagaaagaaaaatacgggttttccatttaagaaatgagatagtgttccacttt
Downstream sequence
ATGTACTAGTATTGCAGATTAGGAAAAAAAAAAAAACCCAGCTCATCTCAAACCCTCGTGGGTCTTTTTGTGTGACATAGAATGAGAGCTGAGCTGAGCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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