VISDB Viral Integration Site DataBase

VIS ID

TVIS10011629

Fusion event

HBV-DUSP22 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

194

Orient

+

Integrated sequence

TTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCT| |CGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACC

Chromosome

chr6

Cytoband

p25.3

Reference genome

Start

End

328351/328351 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-4664-3p ; hsa-mir-1180-3p ; hsa-mir-4497 ; hsa-mir-139-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4691-3p ; hsa-mir-449b-3p ; hsa-mir-6856-3p

Nearest miRNA

hsa-mir-10398/Downstream/1061963;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/35512, chr6-CpG: 261/Downstream/62837

Nearest cancer related gene

DUSP22(TSG, No orient, 0)

Upstream sequence

tggtgacccgaactccagcacatcgatgcagggggtgtcctgcggccattaaaGTGACAGGTCTGAGGGCTCAGTCAATAGCAGGAGACGTGTGTAGGAG

Downstream sequence

CTGGCTGGAGGAAATCCAACATTCTGACCGTGCCCACTTTAGCCTTGCACTGAAATATCTTGAACAAAAATAAGCTTTTGAGTTCTCATCTGTTGATCTG