Fusion event
HBV-GRM8 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
End
126386827/126746773 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/9726454; hsa-mir-10399/Downstream/311315;
Upstream sequence
TTTAAGAAAAAAGAGGATGAGGGGAAATAGAGAGAGAGGAAAGTGAGGAATTTCTTTTGACGACTTTTTGGACAAACTTGCTATTTTAGTTCACTCCCTT
Downstream sequence
tttagatatttaaatatctaaaattGCTCAATAAAGCGCGAAATGTCTTGATAACAATGATCTTTCATACAAGGAATATGCAATATAAATTATACTTCAA
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.