Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011642
Fusion event
HBV-PDE1C integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1815
Orient
-
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
Start
End
32104461/32064849 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1183/Upstream/1774959; hsa-mir-10399/Downstream/668132;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/727921, chr7-CpG: 70/Downstream/5602
Upstream sequence
ACCTGAGGCCCACAGACTGCAGCCTACGCAAGCCCCCCAGTACTGTTCCTGGGAGAGCTGAGATGGAATCCATGTTCTTCCTCTACCTGCTGACACCCCT
Downstream sequence
CAGCCTCTGCCTTCCTTTCCAGCATCACCTCTCATGACTACACTTCTATCTGTCCCTCAGTACTGCACTAGATGAGCTGCAAGAGGACACCACACATTAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.