Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011643
Fusion event
HBV-SGCE integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1824
Orient
-
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
Start
End
94273122/94643810 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/926805; hsa-mir-10399/Downstream/1575852;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/133173, chr7-CpG: 112/Downstream/11736
Upstream sequence
ACCTGAGGCCCACAGACTGCAGCCTACGCAAGCCCCCCAGTACTGTTCCTGGGAGAGCTGAGATGGAATCCATGTTCTTCCTCTACCTGCTGACACCCCT
Downstream sequence
AATTTTCATTAGAAAAGGACCAATGCATTTTTTTATGTGAGAATGGATTTCTCTAGGACGGAAAAATATGACTCAATATTTAAAATATGTATCCTACCTA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.