VISDB Viral Integration Site DataBase

VIS ID

TVIS10011645

Fusion event

HBV-TAF2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2062

Orient

+

Integrated sequence

TCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTG| |CACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAG

Chromosome

chr8

Cytoband

q24.12

Reference genome

Start

End

120839223/119826983 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA8C ; FRA8E

Target gene

miRNAs that regulate target gene

hsa-mir-181a-5p ; hsa-mir-4803 ; hsa-mir-6739-3p ; hsa-mir-375 ; hsa-mir-6844 ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-3148 ; hsa-mir-651-3p

Nearest miRNA

hsa-mir-12123/Upstream/501718; hsa-mir-10400/Downstream/3388805;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/410045, chr8-CpG: 29/Downstream/5575

Upstream sequence

ttttctgggagtttaatcctaaggaaaaccaaggatatacagagaagtatatttataaagctaatcttattgacttgttaaagctcaaaattggcagcaa

Downstream sequence

aggagtttgagaccagcctaagcaacatggcaaaactccgtctctacaaaaaatacaaaaattagccaggctggtggtacgtgcctgtggtcccagctac