Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011659
Fusion event
HBV-DHRS7B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2231
Orient
+
Integrated sequence
AAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTT| |TGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTT
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
Start
End
21082649/21179336 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1180/Upstream/1834762; hsa-mir-10226/Downstream/6114574;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/51835, chr17-CpG: 113/Downstream/34201
Upstream sequence
cctaattaaaaatgatgttgagcatcttttcatgtgcttattgaccatttattaatctttggagaaatgtctattcaaggccaggcactgtggctcatgc
Downstream sequence
ctgtaattccagcactttgggaggccgaggtgagtggatgatcacttgaggccaggagtttgagaccagcctggccaacatgacgaaacccatctctacc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.