VISDB Viral Integration Site DataBase

VIS ID

TVIS10011662

Fusion event

HBV-CLK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1795

Orient

-

Integrated sequence

CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

201722174/200857451 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-186-5p

Nearest miRNA

hsa-mir-10b/Upstream/11724340; hsa-mir-1244-1/Downstream/5925783;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/44868, chr2-CpG: 85/Downstream/6718

Upstream sequence

GAATGGTCAACATTCCAGTCTGCTAGAAAATCACCAGTAACTAAAACTTACTACCTCTTATGAAGCTTTCTTTTATGAGATATATCACGCCTTAATTTTT

Downstream sequence

ACCCAGCATTCGAAGTTACTATTTTTGCGCATCAGAAAAGTCTAAATCATAGTCTGCAACAAAGTACGTTGTTATATGGTGGATATCCTACTTGCTGAAT