Basic Information
VIS ID
TVIS10011665
Fusion event
HBV-chr3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2878
Orient
+
Integrated sequence
ATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCC| |TCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGAC
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
End
44902044/44860552 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/746242; hsa-let-7g/Downstream/1336;
Nearby gene
KIF15(-7296) ; MIR564(+1336) ;
Upstream sequence
ttcacataactctttttacagtgtatcattacagttgttctatgttattattagttattattgttaatctcttactatgtttaatatataaattaaactt
Downstream sequence
agtagagatggagtttcaccatcttgaccaatctggtcttgaactcctgacctcgtaatccacccacctttggcctcccaaagtgctgggattacaggcg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate