VISDB Viral Integration Site DataBase

VIS ID

TVIS10011671

Fusion event

HBV-ZFP36L1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1989

Orient

+

Integrated sequence

GTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGAT| |CTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGG

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

69260812/68794095 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-let-7a-5p ; hsa-mir-423-5p ; hsa-mir-656-3p ; hsa-mir-1277-5p ; hsa-mir-6734-3p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548ar-3p ; hsa-mir-5582-3p ; hsa-mir-548az-3p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-4504 ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-624-3p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-4709-3p ; hsa-mir-376a-5p ; hsa-mir-5190 ; hsa-mir-7852-3p ; hsa-mir-548at-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-498 ; hsa-mir-193b-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3185 ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-7113-5p ; hsa-mir-4441 ; hsa-mir-6754-5p ; hsa-mir-4270 ; hsa-mir-6732-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6507-5p ; hsa-mir-548g-3p ; hsa-mir-6083 ; hsa-mir-3944-5p ; hsa-mir-6499-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-100-3p ; hsa-mir-3977 ; hsa-mir-103a-2-5p ; hsa-mir-382-5p ; hsa-mir-495-5p ; hsa-mir-124-3p ; hsa-mir-3148 ; hsa-mir-4720-3p ; hsa-mir-3910 ; hsa-mir-548an ; hsa-mir-335-3p ; hsa-mir-3074-5p ; hsa-mir-6868-3p ; hsa-mir-3157-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-3667-3p ; hsa-mir-3614-3p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-183-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3140-3p ; hsa-mir-3182 ; hsa-mir-3607-3p ; hsa-mir-3686 ; hsa-mir-4753-3p ; hsa-mir-4768-5p ; hsa-mir-506-3p ; hsa-mir-548av-3p ; hsa-mir-581 ; hsa-mir-6809-3p ; hsa-mir-6832-3p ; hsa-mir-6833-3p ; hsa-mir-8070 ; hsa-mir-96-5p

Nearest miRNA

hsa-mir-208a/Upstream/1352165; hsa-mir-1185-1/Downstream/3722725;

Nearest TSS

Nearest CpG islands

chr14-CpG: 229/Target, None/Upstream, None/Downstream

Upstream sequence

GTTTCTTTTCACGCATCCAATCTTTAAACTTTTTAGTCAAGAAAACCCTAATCCTTCCTGAATGCCCCTTCCTCCCAGAAAAAGCCCACCGAGCAACTCA

Downstream sequence

CTACTTTCCACGCGCGCTCCGAATTCTGGGCGGCGCCACAACCCTCCCTCCTCCTCCATCCTCCCCACACACACCTCAAGACTCTAGAACAATGAAAAAA