Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011682
Fusion event
HBV-ANKS1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2713
Orient
+
Integrated sequence
TGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAA| |CATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTT
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
Start
End
99189274/98795496 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7i/Upstream/800048; hsa-mir-1178/Downstream/1394388;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/49505, chr12-CpG: 142/Downstream/98948
Upstream sequence
TGGATGTCGAGGATGAGAACTGAATAATCTTTGCCTGAAATCACACTACACTCTAGAATTTCCACTCTGGAGAATACTCAGTTCTAACTTGTGATTCCTG
Downstream sequence
GTAGAACAAACTTTATTTTTCTAGCCTAGCAATGATCTAGAAGCAGAGGAATCCCAGTGCCTTTTAAAAGTTATTATGTGGTTTTCTTTTAAAAAGCTCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.