Basic Information
VIS ID
TVIS10011696
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
147
Orient
+
Integrated sequence
CCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCT| |GCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGA
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
End
225667672/225479970 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/1081659; hsa-mir-1182/Downstream/442110;
Nearby gene
LBR(-51115) ; ENAH(+6862) ;
Upstream sequence
gactactgcactccagccttggtgacagagcgagattatgtctcaaaaaaaaaaaaaaaaaaagaaGTggccaggtgcggtggctcatgcctgtaatccc
Downstream sequence
agcactttgggagactgaagcaggcggatcacctgaggttgggagtttaagaccagcctggccaacatagagaatccccatctctactaaaaatacaaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate