VISDB Viral Integration Site DataBase

VIS ID

TVIS10011706

Fusion event

HBV-DDB1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

3110

Orient

+

Integrated sequence

GGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAAT| |CGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG

Chromosome

chr11

Cytoband

q12.2

Reference genome

Start

End

61092485/61325013 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-941 ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-30c-5p ; hsa-mir-26a-5p ; hsa-mir-3200-3p ; hsa-mir-493-3p ; hsa-mir-4330 ; hsa-mir-1304-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-6876-5p ; hsa-mir-5197-3p ; hsa-mir-4476 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n ; hsa-mir-3941 ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-129-2/Upstream/1115857; hsa-let-7a-2/Downstream/183583;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/29422, chr11-CpG: 99/Downstream/7588

Upstream sequence

tgaggcggatggatcacctgaggtcgggagttcaagaccagcctgaccaacatggagaaaccccatctctactaaaaatacaaaattagccgggcgtgat

Downstream sequence

ggcacatgcctgtaatcccagctactaaggaggctgaggcaggagaatcgcctgaacctgggaggcggaggttgcagtgagctgagatcgtgccactgca