VISDB Viral Integration Site DataBase

VIS ID

TVIS10011714

Fusion event

HBV-TSC22D1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1454

Orient

-

Integrated sequence

CCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCG| |GACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGT

Chromosome

chr13

Cytoband

q14.11

Reference genome

Start

End

45107792/44533656 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-100-5p ; hsa-mir-9-3p ; hsa-mir-590-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-6758-5p ; hsa-mir-6856-5p

Nearest miRNA

hsa-mir-2276/Upstream/337456; hsa-mir-1267/Downstream/5462759;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/96397, chr13-CpG: 216/Downstream/42273

Nearest cancer related gene

TSC22D1(TSG, No orient, 0)

Upstream sequence

gtggatcacctgaggtcaggagttcaagacctgcctggccaccatggtgaagccccatctctacaaaaatacataaattagctgagcatgatggcaggtg

Downstream sequence

cctgtaatcccaggtactcgggaggctgaggtgggagaatcacttgaacccaggaggtggtggttgcagtgagctgaggttgccccatggcactccagcc