Basic Information
VIS ID
TVIS10011717
Fusion event
HBV-OTX2-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1750
Orient
-
Integrated sequence
CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG
Host Sequence
Chromosome
chr14
Cytoband
q22.3
Reference genome
End
57379448/56912730 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-208a/Upstream/2034537; hsa-mir-1185-1/Downstream/2734232;
Upstream sequence
taggttcaagcgattctcctcctcagcctccccagtagctgggattacaggcatgtgccaccatgcgcagctaattttttgtatttttagtagagacggg
Downstream sequence
gttctccatgttggtcaggctggtcttgaactcctgacctcaggtgatctgcccgccttggctttccaaagtgctgggattacaggcgtgagccaccgcg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate