VISDB Viral Integration Site DataBase

VIS ID

TVIS10011725

Fusion event

HBV-SMG6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1750

Orient

-

Integrated sequence

CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG

Chromosome

chr17

Cytoband

p13.3

Reference genome

Start

End

2129346/2226052 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-331-3p ; hsa-mir-185-5p ; hsa-mir-93-5p

Nearest miRNA

hsa-mir-132/Upstream/175672; hsa-mir-10226/Downstream/466809;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/166718, chr17-CpG: 100/Downstream/77171

Upstream sequence

cttatgtccaggttatagagagaactcttaagacgtaataataaagacaaacaacttgataaaaaaacaagtgggcactttgggaggctgaggcaggcgg

Downstream sequence

atcgcctgaggtcgggagttcaagaccagcctgaccaacatggagaaaccctgtttctactaaaaatacaaaattagctgggtgtggtggcgcatgcctg