VISDB Viral Integration Site DataBase

VIS ID

TVIS10011738

Fusion event

HBV-TBC1D22A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1747

Orient

-

Integrated sequence

GGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGG| |GAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC

Chromosome

chr22

Cytoband

q13.31

Reference genome

Start

End

47185316/46789419 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-342-5p ; hsa-mir-484 ; hsa-mir-4633-5p ; hsa-mir-532-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-8485

Nearest miRNA

hsa-let-7a-3/Upstream/675651; hsa-mir-12114/Downstream/1484945;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/26336, chr22-CpG: 19/Downstream/4168

Upstream sequence

tttcactgtgttatccaggatggtctcgatctcctgacctcgtgatccgcccgcctcggcctcccGATAAGACTGGGTTtctgtgctcctgtgacatgct

Downstream sequence

cttgtaggaatcatcatagaacagtcaaaatgccagttgaagttttgcttttgtgagtaaactgtaagggccggaatagtttggatgtgttgtgcttacc