VISDB Viral Integration Site DataBase

VIS ID

TVIS10011745

Fusion event

HBV-SH3D19 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1750

Orient

-

Integrated sequence

CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG

Chromosome

chr4

Cytoband

q31.3

Reference genome

Start

End

152075480/151154328 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-128-3p ; hsa-mir-183-5p ; hsa-let-7c-5p ; hsa-mir-7151-5p ; hsa-mir-3942-3p ; hsa-mir-7977 ; hsa-mir-4437 ; hsa-mir-4284 ; hsa-mir-383-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-378a-5p ; hsa-mir-3157-5p ; hsa-mir-1193 ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4485-5p ; hsa-mir-4691-3p ; hsa-mir-2392 ; hsa-mir-6089 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-4696 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-6501-3p ; hsa-mir-451b ; hsa-mir-508-5p ; hsa-mir-4432

Nearest miRNA

hsa-mir-12113/Upstream/3371660; hsa-mir-1305/Downstream/1334999;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/54370, chr4-CpG: 81/Downstream/170711

Upstream sequence

ttataatcaatccctgatctaactcctggttctgctcctctggcagaatcctTATTCTGTCATACTTATTCAATGATGTTTAATAGAGACTTCCGACTCC

Downstream sequence

tctccatgttggtcaggctggtcttgaactcccgacctcaggcgatccgcccgccttggcctcccaaagtgctgggattacaggcttgaaccattgcgcc