Basic Information
VIS ID
TVIS10011750
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1750
Orient
-
Integrated sequence
CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
End
161785596/162358590 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1873140; hsa-mir-103a-1/Downstream/5807255;
Nearby gene
GABRG2(-203051) ; CCNG1(+1078981) ;
Upstream sequence
tgcccaggctggaatgcagtggcactatctcaactcatggcaacctctgcttccctggttcaagtgattctcctggttcatcctctggagtagctgggat
Downstream sequence
gttctccatgttggtcaggctggtcttgaactcccgacctcaggtcatccgcccaccttggcctcccaaagtgctgggattacaagcatgagccaacata
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate