VISDB Viral Integration Site DataBase

VIS ID

TVIS10011751

Fusion event

HBV-DROSHA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1750

Orient

-

Integrated sequence

CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG

Chromosome

chr5

Cytoband

p13.3

Reference genome

Start

End

31498741/31498634 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-760 ; hsa-mir-505-3p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-4290 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6892-3p ; hsa-mir-6872-3p ; hsa-mir-8485 ; hsa-mir-4762-5p ; hsa-mir-216a-5p ; hsa-mir-6516-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-4660 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-148a-5p

Nearest miRNA

hsa-mir-10397/Upstream/14342642; hsa-mir-103a-1/Downstream/437468;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/304322, chr5-CpG: 42/Downstream/33369

Upstream sequence

tgaggtcaggagttcaagaccagcctggccaacatggtgaaaccccgtctctactaaaaatacagaaaattagccaggcgtggtgatgggcacctgtaat

Downstream sequence

atcgcctgaggtcgggagttcaagaccagcctgaccaacatggagaaaccccatctctactaaaaatacaaaattagccaggcgtggtgatgcacgcctg