Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
TTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGA| |TCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAA
End
248411799/248248497 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1046437; hsa-mir-3124/Downstream/577880;
Upstream sequence
CTTTGATGTGGTGCTCtatttttcaaaaattaaaaatttttaaaaGAAATATGGGTATTTCAGCAAaagaaaaaaagggagtgacagagggaggaaggga
Downstream sequence
ggaagaaacggaggaaaaagagaaACACTCCCCGAGATGCTTTCTTGCACATTATATTTTTCACTGTGGCTGTTCAATGGAGATGTCCCGAGGAAACCCA
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.