VISDB Viral Integration Site DataBase

VIS ID

TVIS10011774

Fusion event

HBV-SOX5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1729

Orient

-

Integrated sequence

CCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAA| |GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

24237747/24084813 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-194-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-96-5p ; hsa-mir-130a-3p ; hsa-mir-181a-5p ; hsa-mir-132-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4766-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-574-5p ; hsa-mir-5580-3p ; hsa-mir-555 ; hsa-mir-374a-3p ; hsa-mir-136-3p ; hsa-mir-4704-5p ; hsa-mir-3529-3p ; hsa-mir-6759-5p ; hsa-mir-6793-5p ; hsa-mir-6748-5p ; hsa-mir-933 ; hsa-mir-4783-5p ; hsa-mir-3607-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/6411419; hsa-let-7i/Downstream/127608;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/1459534, chr12-CpG: 92/Downstream/477209

Upstream sequence

AATCATCTTCTCCCTCCCATTTTATTCTAGAACTCCAGTGTAAACCCAAAAGGCATAAACTGCCTTTTAATAGTTGTTCTGTTATGCATAGCCCTAACCT

Downstream sequence

ATCACTACATGTTTTACATTAATACTACAAATGATACATCTTAACTATAGTTATCTTTTTACTAATTGATAAGCTTTATATAATAACAATGATGCTAACA