VISDB Viral Integration Site DataBase

VIS ID

TVIS10011780

Fusion event

HBV-SLC25A21 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1804

Orient

-

Integrated sequence

ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT

Chromosome

chr14

Cytoband

q13.3

Reference genome

Start

End

37455375/36986170 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-625-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-335-3p ; hsa-mir-3611 ; hsa-mir-4289 ; hsa-mir-4666a-3p

Nearest miRNA

hsa-mir-208a/Upstream/33779; hsa-mir-1185-1/Downstream/10774825;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/319027, chr14-CpG: 61/Downstream/185857

Upstream sequence

aatggtatttagaaatcaagatttaggtattagggaggctctttacaactgaaatctctcaggcactctcaatggacaaagcaataaaacatatgcatca

Downstream sequence

tatatacacacatatctatagacatatttttacgtttaattatttctataatctacatattaaaaaccataaattcacagcaatattttcaattccaatc