Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011784
Fusion event
HBV-SLC14A2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1567
Orient
-
Integrated sequence
GGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCA| |TCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTC
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
Start
End
43152174/45572209 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1-2/Upstream/602043; hsa-mir-122/Downstream/1808287;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/508237, chr18-CpG: 37/Downstream/203144
Upstream sequence
TTCCTTTCCTCTGGGGTATCTGAAACTTTGTGATTAGGTCAGTCTTTAAAGCTGTTCAGAGTTAATTAACACATATGCATTTAGACTGGCTCCATTGAGC
Downstream sequence
CAGCCAAGGCAATTCCCAAAATAGAATTCAAGGGTTCAGAACTACCTTCCGTCTTCTTTCCTAAAAGCATGTGATAAGATGCCCCCAACAAATCACCACG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.