VISDB Viral Integration Site DataBase

VIS ID

TVIS10011786

Fusion event

HBV-SPAG16 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

-

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

215090939/214226215 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4713-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-6507-3p ; hsa-mir-6828-5p ; hsa-mir-651-3p ; hsa-mir-3662

Nearest miRNA

hsa-mir-10b/Upstream/468056; hsa-mir-1244-1/Downstream/3674298;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/941513, chr2-CpG: 110/Downstream/583056

Upstream sequence

aacatgaagcacttatgatttctcataagtctcaatggatctcagctctgcttcttcccttgtctgaagtttgctggcaggttggtaggggctagcccgt

Downstream sequence

ctaggatagtcttagctggtatgactcagctctgccccttggattcttctcatagtgaaggtgaaagtacatgggacaaagtgaaaaatgcacatacttt