Basic Information
VIS ID
TVIS10011787
Fusion event
HBV-LOC105374786 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2841
Orient
-
Integrated sequence
GACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGA| |TCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGA
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
End
67871407/67644275 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1301/Upstream/1285947; hsa-mir-10b/Downstream/1459407;
Nearby gene
ETAA1(-233874) ; C1D(+397925) ;
Upstream sequence
CAGGAAGTAGAAAAGGTGGTGACAGATAGAAATGGCAAATGTAAGTGGCCTAAAGAAGAAGGCCTGCAGCAGGCTAGTGTGGCTTAGCATAAAAAGTCTA
Downstream sequence
TATGGTTACCTTTGAGAGCAtcactcactcaatcaatacctacaaagcacctcctaagtgcacagaactaaggtaggtactggagaacagccaataggaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate