VISDB Viral Integration Site DataBase

VIS ID

TVIS10011789

Fusion event

HBV-ILDR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1782

Orient

-

Integrated sequence

TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT

Chromosome

chr3

Cytoband

q13.33

Reference genome

Start

End

121733825/122014978 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4330 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-1303 ; hsa-mir-3674 ; hsa-mir-7977 ; hsa-mir-6832-5p ; hsa-mir-4732-5p ; hsa-mir-1304-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-4307 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-483-5p

Nearest miRNA

hsa-let-7g/Upstream/965263; hsa-mir-12124/Downstream/1146816;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/21520, chr3-CpG: 33/Downstream/7136

Upstream sequence

TTTGGCACTAATCACAGGCTGAATTATTTACATGGGGATAATTTTAAAATCCGTGTTTTGCACCTTCCAGACAAAATTAGAATTATAGTATGTAAACTGC

Downstream sequence

cattcatttattgagtacacactctgagccagtcattagtagaaaataagagatacaggtccctgcactcttggaacttgtgctcctggtaggagagtca