VISDB Viral Integration Site DataBase

VIS ID

TVIS10011790

Fusion event

HBV-ILDR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

754

Orient

+

Integrated sequence

TCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGT| |ATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAG

Chromosome

chr3

Cytoband

q13.33

Reference genome

Start

End

121733844/122014997 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4330 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-1303 ; hsa-mir-3674 ; hsa-mir-7977 ; hsa-mir-6832-5p ; hsa-mir-4732-5p ; hsa-mir-1304-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-4307 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-483-5p

Nearest miRNA

hsa-let-7g/Upstream/965282; hsa-mir-12124/Downstream/1146797;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/21539, chr3-CpG: 33/Downstream/7117

Upstream sequence

ATCACTATCACCACCACTAGCACGTAATGAATGTTAACAACTGGCCTTTCCctgggctatgcatctcatacacattatctcctttaatctgcaagttaac

Downstream sequence

cactctgagccagtcattagtagaaaataagagatacaggtccctgcactcttggaacttgtgctcctggtaggagagtcaatgataaacaagtaaacac