Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011792
Fusion event
HBV-ALDH1L1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1822
Orient
-
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
End
125873672/126154829 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/364277; hsa-mir-12124/Downstream/1420437;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/70414, chr3-CpG: 73/Downstream/24990
Upstream sequence
ggtgattgaattatgggggcaggtctttacttcactgttctcatgatagttgataagtctcacaagatctgatggttttaaaaatgggagtttctctgca
Downstream sequence
GGGCTGAGCAGACTTCAGAATGGTTTGGGGAAGATAATGTTCTGTTGCTGTCAAGATGGCCCAGACCCTACACAGAGGCCCCAGCACAATGTACTCAGGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.