Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011803
Fusion event
HBV-ALB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2919
Orient
-
Integrated sequence
CACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCA| |GAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCAC
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
Start
End
74275544/73409827 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7132899; hsa-mir-1243/Downstream/3163741;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/150414, chr4-CpG: 20/Downstream/210500
Upstream sequence
tctgcgcagcaaaagaaactaccctcagagtgaacaggcagcctacagaatgggagaaaatttttgcaatctatccgtttgacaaagggctaatatccag
Downstream sequence
TTTTTAGTAGGGAGGGAATTCAAAGTAGAGAATTTTACTGCATCTAGATGCCTGAGTTCATGCATTCATTCCATAAATATATATTATGGAATGCTTTATT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.